Clinical DNA Testing Services

DNA Fingerprint Panel

 

     PreventionGenetics has extensive experience in the use of genetic markers for a variety of research and clinical purposes. PreventionGenetics expects to analyze over 2 million unique molecular marker profiles in 2005. The PreventionGenetics fingerprint panel consists of a unique proprietary grouping of 15 multiallelic polymorphic STRP and in/del markers distributed throughout the genome. The allele patterns generated by these 15 markers for each person tested are virtually unique.

Zygosity testing at PreventionGenetics.

The PreventionGenetics fingerprint panel is used to differentiate between dizygotic (fraternal) or monozygotic (identical) births. The 15 marker panel used at PreventionGenetics provides for a high degree of reliability. Twinning can occur as often as one in sixty births. Zygosity testing can also be done in other multiple births (triplets, quadruplets, etc.) Zygosity testing is useful in tracking genetic disease susceptibility (with monozygotic siblings being at higher risk if one is affected) and for matching compatible donors for organ/tissue transplant (with identical sibs usually providing the best possible match.)

Parentage testing at PreventionGenetics.

There are a number of reasons for needing to know the parental relationship between a child and his or her parents. Most of these are social but increasingly there are real medical needs for this information. The PreventionGenetics fingerprint panel can also be used to determine the likelihood that an adult and child are related to one another. Again the 15 marker PreventionGenetics fingerprint panel provides for a unique profile greatly enhancing the reliability of our parentage testing.

Laboratory Specimen Matching.

The PreventionGenetics fingerprint panel can also be used any time there is a need to identify a particular DNA sample. In the laboratory, this might be used to confirm the identity of multiple DNA samples that presumably come from a specific patient/participant. Determining the specific genetic identity of a particular specimen greatly reduces the risk of sample reporting errors due to a mislabeled sample.