Research
Genotyping
PreventionGenetics
performs genotyping of human DNA polymorphisms in support of biomedical
research. We type both multiallelic (microsatellite/STRP) and
diallelic (SNP and indel) polymorphisms. We preform both whole
genome scans and fine mapping. PreventionGenetics will undertake
projects of any size.
We emphasize low genotyping
costs. See our Price List to calculate
the cost of your project. Genotyping prices are as low as $0.35
per genotype for STRPs and $0.05 per genotype for SNPs. Assay
development fees are usually waived for any markers we have previously
typed (see Marker List).
One
of our specialties is the whole genome polymorphism scan. As standard
scans, we offer 400 STRP (10 cM) and 800 STRP (5 cM) tests. However,
we can readily supplement these standard scans with additional
markers, especially including a newly created set of 800 diallelic
indels.
For
fine mapping, we offer genotyping of nearly all human DNA polymorphisms
including any of about 200,000 STRPs, 800,000 diallelic indels,
and 12 million SNPs.
PreventionGenetics
understands genotyping quality. Genotyping error rates are typically
under 0.5% and with clean genomic DNA, genotyping completion rates
are > 98%.
Experience
of our staff in human genotyping is second to none. PreventionGenetics
personnel have been performing genome scans for disease gene mapping
and other purposes for over 15 years. We have assisted in the
mapping of hundred of disease genes. In addition, we have identified
and characterized many thousands of human DNA polymorphisms, constructed
some of the most widely used human genetic maps, and assembled
many human genome screening sets of markers.
PreventionGenetics
will also store your research DNA samples. We offer continuously
monitored freezers with multiple backup systems and remote storage
of secondary aliquots.