DNA Fingerprint Panel
PreventionGenetics has extensive experience in the use
of genetic markers for a variety of research and clinical purposes. PreventionGenetics
expects to analyze over 2 million unique molecular marker profiles in
2005. The PreventionGenetics fingerprint panel consists of a unique proprietary
grouping of 16 multiallelic polymorphic STRP and in/del markers distributed
throughout the genome. The allele patterns generated by these 16 markers
for each person tested are virtually unique.
Zygosity testing at PreventionGenetics.
The PreventionGenetics fingerprint panel is used to
differentiate between dizygotic (fraternal) or monozygotic (identical)
births. The 16 marker panel used at PreventionGenetics provides for
a high degree of reliability. Twinning can occur as often as one in
sixty births. Zygosity testing can also be done in other multiple births
(triplets, quadruplets, etc.) Zygosity testing is useful in tracking
genetic disease susceptibility (with monozygotic siblings being at higher
risk if one is affected) and for matching compatible donors for organ/tissue
transplant (with identical sibs usually providing the best possible
match.)
Parentage testing at PreventionGenetics.
There are a number of reasons for needing to know the
parental relationship between a child and his or her parents. Most of
these are social but increasingly there are real medical needs for this
information. The PreventionGenetics fingerprint panel can also be used
to determine the likelihood that an adult and child are related to one
another. Again the 16 marker PreventionGenetics fingerprint panel provides
for a unique profile greatly enhancing the reliability of our parentage
testing.
Laboratory Specimen Matching.
The PreventionGenetics fingerprint panel can also be
used any time there is a need to identify a particular DNA sample. In
the laboratory, this might be used to confirm the identity of multiple
DNA samples that presumably come from a specific patient/participant.
Determining the specific genetic identity of a particular specimen greatly
reduces the risk of sample reporting errors due to a mislabeled sample.
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